Buffalo Cauliflower Grilled Cheese

Featured in: Cozy Weeknight Dinners

This sandwich highlights roasted cauliflower tossed in a spicy buffalo wing sauce layered with a creamy ranch spread, sharp cheddar, and mozzarella cheeses. The combination is grilled between buttered sourdough slices until golden and melty. Easy to prepare in under 40 minutes, this flavorful main dish offers a vegetarian option filled with a balanced blend of spice, creaminess, and crunch.

Updated on Fri, 28 Nov 2025 08:14:00 GMT
Golden-brown Buffalo Cauliflower Ranch Grilled Cheese, oozing melted cheese and spicy cauliflower. Save
Golden-brown Buffalo Cauliflower Ranch Grilled Cheese, oozing melted cheese and spicy cauliflower. | toastybloom.com

A bold, flavorful twist on classic grilled cheese: spicy roasted cauliflower, creamy ranch, and gooey melted cheese between crispy golden bread slices.

I first served this to my family on a chilly evening and it instantly became our favorite comfort food.

Ingredients

  • Buffalo Cauliflower: 3 cups small cauliflower florets, 2 tablespoons olive oil, 1/2 teaspoon garlic powder, 1/2 teaspoon smoked paprika, 1/4 teaspoon salt, 1/4 teaspoon black pepper, 1/3 cup buffalo wing sauce
  • Ranch Spread: 1/2 cup ranch dressing (store-bought or homemade), 1 tablespoon chopped fresh chives (optional), 1 tablespoon chopped fresh dill (optional)
  • Sandwiches: 8 slices sourdough or country-style bread, 2 cups shredded sharp cheddar cheese, 1 cup shredded mozzarella cheese, 2 tablespoons unsalted butter softened

Instructions

Preheat Oven:
Preheat oven to 425°F (220°C). Line a baking sheet with parchment paper.
Prepare Cauliflower:
In a bowl, toss cauliflower florets with olive oil, garlic powder, smoked paprika, salt, and black pepper. Spread on the prepared baking sheet.
Roast Cauliflower:
Roast cauliflower for 15 minutes, stirring halfway through. Remove from oven, toss with buffalo wing sauce, and roast 5 more minutes. Set aside.
Mix Ranch:
In a small bowl, mix ranch dressing with chives and dill if using.
Prepare Bread:
Lay out bread slices. Spread ranch mixture on one side of each slice.
Assemble Sandwiches:
On four slices, sprinkle half the cheddar and mozzarella. Top with buffalo cauliflower, then the remaining cheese. Cover with remaining bread slices, ranch-side down.
Butter Bread:
Heat a large skillet or griddle over medium heat. Spread butter on the outer sides of each sandwich.
Grill:
Grill sandwiches 3 to 4 minutes per side, pressing gently, until bread is golden and cheese is melted.
Serve:
Let cool for 1 minute, slice, and serve warm.
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My kids love gathering around the table for this sandwich; it has become our cozy weekend tradition.

Required Tools

Baking sheet, Mixing bowls, Skillet or griddle, Spatula, Knife and cutting board

Allergen Information

Contains Wheat (bread), Milk (cheese, butter, ranch). Ranch dressing may contain eggs or soy; check labels if sensitive. For gluten-free use gluten-free bread. For vegan use plant-based cheese butter and ranch.

Nutritional Information

Calories 430. Total Fat 27 g. Carbohydrates 35 g. Protein 13 g.

Hearty, homemade Buffalo Cauliflower Ranch Grilled Cheese, showcasing crispy bread and a cheesy, veggie filling. Save
Hearty, homemade Buffalo Cauliflower Ranch Grilled Cheese, showcasing crispy bread and a cheesy, veggie filling. | toastybloom.com

This sandwich is perfect for game day or any casual meal, delivering bold flavors with every bite.

Recipe FAQs

How do I roast cauliflower for best flavor?

Toss cauliflower florets with olive oil, garlic powder, smoked paprika, salt, and pepper before roasting at 425°F. Roast for 15 minutes, stir, then roast 5 more minutes after adding buffalo sauce to develop maximum flavor.

Can I use a different type of bread?

Sourdough or country-style bread work best for crispiness and structure, but other sturdy breads like ciabatta or rye can be used.

Is it necessary to butter the sandwich before grilling?

Spreading butter on the outer bread surfaces ensures a golden, crispy crust and helps cheese melt evenly during grilling.

What can I add to increase the spice level?

Drizzle additional buffalo sauce on the cauliflower before assembling or add sliced jalapeños inside for extra heat.

Are there vegetarian options for the cheese and ranch?

Yes, plant-based cheeses and vegan ranch dressings can be substituted to maintain creamy textures while keeping the dish vegetarian-friendly.

Buffalo Cauliflower Grilled Cheese

A bold twist featuring roasted spicy cauliflower, creamy ranch, melted cheeses, and crispy golden bread slices.

Prep Time
15 minutes
Time for Cooking
20 minutes
Complete Time
35 minutes
Recipe Creator Grace Miller

Recipe Group Cozy Weeknight Dinners

Skill Level Easy

Cuisine Type American

Servings Made 4 Portion Count

Dietary Notes Meat-Free

What You Need

Buffalo Cauliflower

01 3 cups small cauliflower florets
02 2 tablespoons olive oil
03 1/2 teaspoon garlic powder
04 1/2 teaspoon smoked paprika
05 1/4 teaspoon salt
06 1/4 teaspoon black pepper
07 1/3 cup buffalo wing sauce

Ranch Spread

01 1/2 cup ranch dressing
02 1 tablespoon chopped fresh chives (optional)
03 1 tablespoon chopped fresh dill (optional)

Sandwiches

01 8 slices sourdough or country-style bread
02 2 cups shredded sharp cheddar cheese
03 1 cup shredded mozzarella cheese
04 2 tablespoons unsalted butter, softened

Step-by-Step Directions

Step 01

Preheat Oven: Set oven to 425°F and line a baking sheet with parchment paper.

Step 02

Season Cauliflower: Toss cauliflower florets with olive oil, garlic powder, smoked paprika, salt, and pepper; spread evenly on baking sheet.

Step 03

Initial Roast: Roast cauliflower for 15 minutes, stirring halfway through.

Step 04

Buffalo Sauce Toss and Roast: Remove cauliflower from oven, toss with buffalo wing sauce, then roast an additional 5 minutes; set aside.

Step 05

Prepare Ranch Spread: Combine ranch dressing with chives and dill if using.

Step 06

Assemble Sandwiches: Spread ranch mixture on one side of each bread slice; layer half the cheddar and mozzarella on four slices, top with buffalo cauliflower, then remaining cheese and bread slices, ranch side down.

Step 07

Butter Bread: Spread softened butter on the outsides of each assembled sandwich.

Step 08

Grill Sandwiches: Heat skillet or griddle over medium heat and grill sandwiches 3–4 minutes per side, pressing gently, until bread is golden and cheese is melted.

Step 09

Serve: Allow sandwiches to cool for 1 minute before slicing and serving warm.

Tools You'll Need

  • Baking sheet
  • Mixing bowls
  • Skillet or griddle
  • Spatula
  • Knife and cutting board

Allergy Details

Look over every item for allergens. If unsure, check with your healthcare provider.
  • Contains wheat (bread), milk (cheese, butter, ranch).
  • Ranch dressing may contain eggs or soy; verify labels if sensitive.
  • For gluten-free option, substitute gluten-free bread.
  • For vegan adaptation, use plant-based cheese, butter, and ranch.

Nutrition (per portion)

For guidance only: not a replacement for professional medical counsel.
  • Energy (Calories): 430
  • Fats: 27 g
  • Carbohydrates: 35 g
  • Proteins: 13 g